HitPredict

Interactor 1: Q86V38 (Q86V38)
Atrophin 1
Gene: ATN1

Interactor 2: PITX2 (Q99697)
Pituitary homeobox 2 (ALL1-responsive protein ARP1) (Homeobox protein PITX2) (Paired-like homeodomain transcription factor 2) (RIEG bicoid-related homeobox transcription factor) (Solurshin)
Gene: PITX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1191 Hs			1 317
+	Hs
		869519 ATN1_HUMAN (1-1191): 5.11e-149: 480: 99.83		PITX2_HUMAN (1-317): 6.82e-70: 221: 100.00
+	Hs
		941923 Q86V38_HUMAN (1-1191): 9.89e-151: 485: 100.00		PITX1_HUMAN (11-311): 7.1e-42: 148: 58.97
+	Hs
		869449 ATN1_HUMAN (1-1191): 5.11e-149: 480: 99.83		PITX1_HUMAN (11-311): 7.1e-42: 148: 58.97
+	Hs
		1200894 Q86V38_HUMAN (1-1191): 9.89e-151: 485: 100.00		LMX1A_HUMAN (4-248): 1.52e-30: 120: 20.38
+	Hs
		641482 KMT2C_HUMAN (4-711): 6.35e-12: 72.6: 10.59		PAX6_HUMAN (55-270): 1.59e-40: 148: 24.36
+	Hs
		620175 KMT2C_HUMAN (4-711): 6.35e-12: 72.6: 10.59		PAX7_HUMAN (2-315): 2.92e-39: 146: 25.92
+	Hs
		203210 SYNJ1_HUMAN (481-1012): 4.33e-10: 66.4: 12.68		PAX6_HUMAN (55-270): 1.59e-40: 148: 24.36
+	Hs
		131694 BCL9_HUMAN (105-767): 6.3e-10: 65.9: 11.16		PAX6_HUMAN (55-270): 1.59e-40: 148: 24.36
+	Hs
		1349418 CHD7_HUMAN (183-895): 1.4e-09: 64.9: 9.92		VSX1_HUMAN (54-206): 5.19e-41: 148: 33.33
+	Hs
		641583 CHD7_HUMAN (183-895): 1.4e-09: 64.9: 9.92		PAX6_HUMAN (55-270): 1.59e-40: 148: 24.36
+	Hs
		131691 BCL9_HUMAN (105-767): 6.3e-10: 65.9: 11.16		PAX7_HUMAN (2-315): 2.92e-39: 146: 25.92
+	Hs
		620215 CHD7_HUMAN (183-895): 1.4e-09: 64.9: 9.92		PAX7_HUMAN (2-315): 2.92e-39: 146: 25.92
+	Hs
		641457 SRCAP_HUMAN (20-543): 6.13e-09: 62.7: 15.21		PAX6_HUMAN (55-270): 1.59e-40: 148: 24.36
+	Mm
		292012 F186A_MOUSE (346-982): 4.14e-13: 76.4: 9.52		LMX1B_MOUSE (4-263): 2.24e-34: 131: 17.31
+	Hs
		822650 KMT2C_HUMAN (4-711): 6.35e-12: 72.6: 10.59		LHX1_HUMAN (4-289): 2.23e-30: 120: 16.07
+	Hs
		131702 BCL9_HUMAN (105-767): 6.3e-10: 65.9: 11.16		LHX1_HUMAN (4-289): 2.23e-30: 120: 16.07
+	Hs
		822688 CHD7_HUMAN (183-895): 1.4e-09: 64.9: 9.92		LHX1_HUMAN (4-289): 2.23e-30: 120: 16.07