Interactor 1: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4
Interactor 2: TLR5 (O60602)
Toll-like receptor 5 (Toll/interleukin-1 receptor-like protein 3)
Gene: TLR5
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12794153 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_1~LRR_4, LRR_4~LRR_8, LRR_1~LRR_6, LRR_6~LRR_8, LRR_1~LRR_8, LRR_8~LRR_8, TIR~TIR |
| Common GO terms | GO:0002224 - toll-like receptor signaling pathway GO:0004888 - transmembrane signaling receptor activity GO:0005886 - plasma membrane GO:0006954 - inflammatory response GO:0032757 - positive regulation of interleukin-8 production and 3 others more... |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
