HitPredict

Interactor 1: FHI2B (Q86V87)
FHF complex subunit HOOK-interacting protein 2B (FHIP2B) (Retinoic acid-induced protein 16)
Gene: FHIP2B

Interactor 2: HOOK3 (Q86VS8)
Protein Hook homolog 3 (h-hook3) (hHK3)
Gene: HOOK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.50	0.567

Property	Details
Experiments	34882091, 28718761
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 743 Hs			1 718
+	Hs
		1201247 FHI2B_HUMAN (1-743): 0: 1097: 100.00		HOOK2_HUMAN (6-718): 8.03e-39: 155: 45.95
+	Hs
		1201252 FHI2B_HUMAN (1-743): 0: 1097: 100.00		HOOK1_HUMAN (196-712): 4.3e-14: 78.1: 12.98
+	Hs
		1139922 FHI2A_HUMAN (1-726): 0: 938: 50.26		HOOK3_HUMAN (1-718): 3.74e-57: 209: 100.00
+	Hs
		1139932 FHI2A_HUMAN (1-726): 0: 938: 50.26		HOOK2_HUMAN (6-718): 8.03e-39: 155: 45.95
+	Hs
		1139940 FHI2A_HUMAN (1-726): 0: 938: 50.26		HOOK1_HUMAN (196-712): 4.3e-14: 78.1: 12.98
+	Hs
		1202428 FHI1B_HUMAN (6-551): 2.56e-163: 498: 21.40		HOOK3_HUMAN (1-718): 3.74e-57: 209: 100.00
+	Hs
		1235420 FHI1B_HUMAN (6-551): 2.56e-163: 498: 21.40		HOOK2_HUMAN (6-718): 8.03e-39: 155: 45.95
+	Hs
		725201 FHI1B_HUMAN (6-551): 2.56e-163: 498: 21.40		MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71
+	Hs
		1235427 FHI1B_HUMAN (6-551): 2.56e-163: 498: 21.40		HOOK1_HUMAN (196-712): 4.3e-14: 78.1: 12.98
+	Hs
		724917 FHI1B_HUMAN (6-551): 2.56e-163: 498: 21.40		MYH9_HUMAN (23-360): 8.18e-09: 61.5: 11.27
+	Hs
		985760 FHI1A_HUMAN (7-581): 6.46e-104: 343: 17.98		HOOK3_HUMAN (1-718): 3.74e-57: 209: 100.00
+	Hs
		985761 FHI1A_HUMAN (7-581): 6.46e-104: 343: 17.98		HOOK2_HUMAN (6-718): 8.03e-39: 155: 45.95
+	Hs
		985765 FHI1A_HUMAN (7-581): 6.46e-104: 343: 17.98		HOOK1_HUMAN (196-712): 4.3e-14: 78.1: 12.98