HitPredict

Interactor 1: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Interactor 2: SRS12 (Q8WXF0)
Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19)
Gene: SRSF12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 29298432, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 953 Hs			1 261
+	Hs
		1201760 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		PPIE_HUMAN (10-98): 7.46e-34: 126: 33.71
+	Hs
		267016 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		SRS10_HUMAN (1-229): 6.35e-34: 125: 50.00
+	Hs
		1201788 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		RBMX2_HUMAN (12-261): 2.44e-31: 119: 18.00
+	Hs
		201686 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		MSI1H_HUMAN (2-95): 2.87e-22: 96: 26.60
+	Hs
		952022 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		SRSF3_HUMAN (1-92): 1.68e-23: 95: 32.61
+	Hs
		964019 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		SRSF2_HUMAN (4-90): 1.12e-22: 94.6: 45.65
+	Hs
		516580 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		PABP1_HUMAN (2-101): 3.98e-19: 88.3: 17.00
+	Hs
		1084321 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		SRSF7_HUMAN (1-108): 2.53e-09: 58.2: 35.78
+	Hs
		1246388 THOC2_HUMAN (248-635): 6.8e-20: 98.2: 14.15		PPIE_HUMAN (10-98): 7.46e-34: 126: 33.71
+	Hs
		1357564 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		PPIE_HUMAN (10-98): 7.46e-34: 126: 33.71
+	Hs
		267100 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		SRS10_HUMAN (1-229): 6.35e-34: 125: 50.00
+	Hs
		1222876 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		PPIE_HUMAN (10-98): 7.46e-34: 126: 33.71
+	Hs
		952179 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		SRSF3_HUMAN (1-92): 1.68e-23: 95: 32.61
+	Hs
		516749 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		PABP1_HUMAN (2-101): 3.98e-19: 88.3: 17.00
+	Hs
		952031 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		SRSF3_HUMAN (1-92): 1.68e-23: 95: 32.61
+	Hs
		964025 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		SRSF2_HUMAN (4-90): 1.12e-22: 94.6: 45.65
+	Hs
		1031405 TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54		PABP4_HUMAN (2-101): 2.19e-20: 92.1: 18.00
+	Hs
		516609 TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54		PABP1_HUMAN (2-101): 3.98e-19: 88.3: 17.00
+	Hs
		1084451 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		SRSF7_HUMAN (1-108): 2.53e-09: 58.2: 35.78
+	Hs
		1084330 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		SRSF7_HUMAN (1-108): 2.53e-09: 58.2: 35.78