Interactor 1: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4

Interactor 2: TRIL (Q7L0X0)
TLR4 interactor with leucine rich repeats (Leucine-rich repeat-containing protein KIAA0644)
Gene: TRIL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 19710467
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_4~LRR_8, LRR_6~LRR_8, LRR_8~LRR_8
Common GO terms GO:0001530 - lipopolysaccharide binding
GO:0006954 - inflammatory response
GO:0034142 - toll-like receptor 4 signaling pathway
GO:0045087 - innate immune response
GO:0046696 - lipopolysaccharide receptor complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 839
Hs

1 811
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024