HitPredict

Interactor 1: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Interactor 2: CLK4 (Q9HAZ1)
Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)
Gene: CLK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 953 Hs			1 481
+	Hs
		833765 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		CLK1_HUMAN (1-480): 1.32e-146: 429: 78.72
+	Hs
		833914 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		CLK2_HUMAN (1-481): 3.95e-131: 390: 55.26
+	Hs
		834073 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		CLK3_HUMAN (8-481): 1.82e-128: 388: 52.19
+	Hs
		1201571 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		DYRK2_HUMAN (18-477): 7.35e-113: 347: 24.32
+	Hs
		414977 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		CDK1_HUMAN (156-481): 2.47e-115: 343: 23.95
+	Hs
		1335031 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		CLK4_HUMAN (1-481): 3.31e-154: 449: 100.00
+	Hs
		833803 MINT_HUMAN (8-923): 2.4e-20: 99.8: 10.24		CLK1_HUMAN (1-480): 1.32e-146: 429: 78.72
+	Hs
		833836 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		CLK1_HUMAN (1-480): 1.32e-146: 429: 78.72
+	Hs
		833769 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		CLK1_HUMAN (1-480): 1.32e-146: 429: 78.72
+	Hs
		833993 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		CLK2_HUMAN (1-481): 3.95e-131: 390: 55.26
+	Hs
		834148 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		CLK3_HUMAN (8-481): 1.82e-128: 388: 52.19
+	Hs
		625642 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		CDK2_HUMAN (156-480): 1.38e-132: 387: 24.40
+	Hs
		833918 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		CLK2_HUMAN (1-481): 3.95e-131: 390: 55.26
+	Hs
		3286 A0A0S2Z4Z6_HUMAN (97-903): 3.62e-14: 79: 10.66		CLK2_HUMAN (1-481): 3.95e-131: 390: 55.26
+	Hs
		834079 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		CLK3_HUMAN (8-481): 1.82e-128: 388: 52.19
+	Hs
		625528 TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54		CDK2_HUMAN (156-480): 1.38e-132: 387: 24.40
+	Hs
		1044321 PCLO_HUMAN (54-952): 1.43e-31: 136: 7.21		DYR1A_HUMAN (113-476): 2.18e-103: 327: 29.02
+	Hs
		1268608 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		DYRK2_HUMAN (18-477): 7.35e-113: 347: 24.32
+	Hs
		1264773 TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54		DYRK2_HUMAN (18-477): 7.35e-113: 347: 24.32
+	Hs
		1043978 THOC2_HUMAN (248-635): 6.8e-20: 98.2: 14.15		DYR1A_HUMAN (113-476): 2.18e-103: 327: 29.02