Interactor 1: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4

Interactor 2: TREM1 (Q9NP99)
Triggering receptor expressed on myeloid cells 1 (TREM-1) (Triggering receptor expressed on monocytes 1) (CD antigen CD354)
Gene: TREM1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17098818
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_4~V-set, LRR_8~V-set
Common GO terms GO:0004888 - transmembrane signaling receptor activity
GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0038023 - signaling receptor activity
GO:0045087 - innate immune response
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 839
Hs

1 234
+ Mm

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Last updated: 15 Jul 2024