HitPredict

Interactor 1: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 29298432
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0016607 - nuclear speck
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 953 Hs			1 2752
+	Hs
		1222878 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		1201616 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		MINT_HUMAN (709-2695): 5.55e-37: 157: 9.30
+	Hs
		820965 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		1201807 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11
+	Hs
		1246354 THOC2_HUMAN (248-635): 6.8e-20: 98.2: 14.15		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		807752 MAP1S_HUMAN (406-876): 1.83e-13: 77: 16.80		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13
+	Hs
		807690 ANK2_HUMAN (498-952): 3.04e-11: 70.1: 14.63		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13
+	Dm
		1376672 FUTSC_DROME (3-953): 6.99e-26: 117: 12.14		FUTSC_DROME (149-2601): 1.34e-21: 106: 12.75
+	Mm
		1351630 PCLO_MOUSE (336-952): 4.64e-24: 112: 9.12		PCLO_MOUSE (8-2704): 3.33e-19: 98.2: 7.94
+	Dm
		65570 FUTSC_DROME (3-953): 6.99e-26: 117: 12.14		A8JNM5_DROME (1486-2593): 8.81e-10: 67.1: 11.55
+	Hs
		1264771 TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		1303336 MUC4_HUMAN (4-943): 3.75e-10: 66.6: 9.72		MUC4_HUMAN (1029-2712): 5.23e-22: 107: 13.82
+	Dm
		113976 M9PB30_DROME (374-952): 2.15e-16: 87.1: 7.48		M9PB30_DROME (2292-2752): 2.57e-14: 82: 11.45
+	Hs
		152668 KMT2D_HUMAN (379-947): 6.05e-11: 69: 11.30		BD1L1_HUMAN (16-2752): 1.77e-19: 99.2: 9.13
+	Hs
		1056897 MDC1_HUMAN (9-950): 1.49e-09: 64.4: 9.73		BD1L1_HUMAN (16-2752): 1.77e-19: 99.2: 9.13
+	Hs
		1154038 NIPBL_HUMAN (485-927): 6.3e-11: 68.9: 15.90		NIPBL_HUMAN (333-1474): 1.68e-16: 89.1: 14.39
+	Hs
		152665 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		152667 KMT2D_HUMAN (379-947): 6.05e-11: 69: 11.30		KMT2C_HUMAN (1760-2747): 2.06e-09: 65.9: 9.01