Interactor 1: VPS36 (Q86VN1)
Vacuolar protein-sorting-associated protein 36 (ELL-associated protein of 45 kDa) (ESCRT-II complex subunit VPS36)
Gene: VPS36

Interactor 2: SNF8 (Q96H20)
Vacuolar-sorting protein SNF8 (ELL-associated protein of 30 kDa) (ESCRT-II complex subunit VPS22) (hVps22)
Gene: SNF8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 28514442, 32296183, 33961781, 35271311, 16371348, 18539118, 16973552, 14505570, 17010938, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, x-ray crystallography, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains EAP30~EAP30
Common GO terms GO:0000814 - ESCRT II complex
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0016236 - macroautophagy
GO:0031902 - late endosome membrane
and 4 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 386
Hs

1 258
+ At
+ Hs
+ At
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024