Interactor 1: VPS36 (Q86VN1)
Vacuolar protein-sorting-associated protein 36 (ELL-associated protein of 45 kDa) (ESCRT-II complex subunit VPS36)
Gene: VPS36
Interactor 2: VPS25 (Q9BRG1)
Vacuolar protein-sorting-associated protein 25 (hVps25) (Dermal papilla-derived protein 9) (ELL-associated protein of 20 kDa) (ESCRT-II complex subunit VPS25)
Gene: VPS25
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.975 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 35271311, 16371348, 18539118, 16973552, 32296183, 33961781, 14505570, 17010938, unassigned1304 |
| Identification Methods | affinity chromatography technology, two hybrid, x-ray crystallography, pull down, anti tag coimmunoprecipitation, validated two hybrid, two hybrid array, two hybrid prey pooling approach |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EAP30~ESCRT-II |
| Common GO terms | GO:0000814 - ESCRT II complex GO:0005634 - nucleus GO:0005829 - cytosol GO:0016236 - macroautophagy GO:0036258 - multivesicular body assembly and 3 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
