HitPredict

Interactor 1: VPS36 (Q86VN1)
Vacuolar protein-sorting-associated protein 36 (ELL-associated protein of 45 kDa) (ESCRT-II complex subunit VPS36)
Gene: VPS36

Interactor 2: VPS28 (Q9UK41)
Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28)
Gene: VPS28

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

The method score is based on:

Property	Details
Experiments	17215868, 18539118
Identification Methods	x-ray crystallography, affinity chromatography technology
Interaction Type	association, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005768 - endosome GO:0005829 - cytosol GO:0016236 - macroautophagy GO:0031902 - late endosome membrane GO:0036258 - multivesicular body assembly and 4 others more... GO:0043130 - ubiquitin binding GO:0043328 - protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0070062 - extracellular exosome GO:0090148 - membrane fission
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	386
Hs

1	221

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024