Interactor 1: TAXB1 (Q86VP1)
Tax1-binding protein 1 (TRAF6-binding protein)
Gene: TAX1BP1

Interactor 2: ITCH (Q96J02)
E3 ubiquitin-protein ligase Itchy homolog (Itch) (EC 2.3.2.26) (Atrophin-1-interacting protein 4) (AIP4) (HECT-type E3 ubiquitin transferase Itchy homolog) (NFE2-associated polypeptide 1) (NAPP1)
Gene: ITCH

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.601

The method score is based on:

Property Details
Experiments 18246070, 33545068
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0031410 - cytoplasmic vesicle
GO:0032088 - negative regulation of NF-kappaB transcription factor activity
and 4 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 789
Hs

1 903
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024