Interactor 1: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4
Interactor 2: LY96 (Q9Y6Y9)
Lymphocyte antigen 96 (Ly-96) (ESOP-1) (Protein MD-2)
Gene: LY96
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.987 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11976338, 10359581, 22474354, 19252480, 22532668, 19060881, 11435474, 15557191, 17056597, 16272300, 11160242, 15694388, 14607928, 12960171, 15728506, 11593030, 22433852, 17803912, 20547845 |
| Identification Methods | affinity chromatography technology, solid phase assay, molecular sieving, x-ray crystallography, x ray scattering, anti tag coimmunoprecipitation, surface plasmon resonance, nuclear magnetic resonance, cross-linking study |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | E1_DerP2_DerF2~LRR_8 |
| Common GO terms | GO:0001530 - lipopolysaccharide binding GO:0001875 - lipopolysaccharide immune receptor activity GO:0002224 - toll-like receptor signaling pathway GO:0005886 - plasma membrane GO:0006954 - inflammatory response and 9 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
