HitPredict

Interactor 1: CAND1 (Q86VP6)
Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (TBP-interacting protein of 120 kDa A) (TBP-interacting protein 120A) (p120 CAND1)
Gene: CAND1

Interactor 2: PUF60 (Q9UHX1)
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1)
Gene: PUF60

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1230 Hs			1 559
+	Hs
		1054412 CAND1_HUMAN (1-1230): 0: 922: 100.00		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1020285 CAND1_HUMAN (1-1230): 0: 922: 100.00		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		1031380 CAND1_HUMAN (1-1230): 0: 922: 100.00		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		516581 CAND1_HUMAN (1-1230): 0: 922: 100.00		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		268893 SF3B1_HUMAN (365-1153): 1.41e-55: 214: 12.32		PUF60_HUMAN (1-559): 2.1e-103: 324: 100.00
+	Hs
		268715 SF3B1_HUMAN (365-1153): 1.41e-55: 214: 12.32		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Ce
		248174 O62332_CAEEL (609-1197): 5.34e-13: 75.8: 13.51		Q20084_CAEEL (97-553): 2.1e-76: 250: 17.65
+	Hs
		1054475 GCN1_HUMAN (8-396): 2.82e-11: 70.4: 12.69		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Dm
		597086 Q9VN44_DROME (175-1181): 1.96e-27: 123: 11.69		PABP_DROME (470-550): 1.89e-09: 62.2: 9.88
+	Sc
		376762 IMB2_YEAST (445-964): 4.58e-11: 69.5: 14.81		PABP_YEAST (465-553): 7.06e-12: 69.9: 16.85