HitPredict

Interactor 1: RETR3 (Q86VR2)
Reticulophagy regulator 3
Gene: RETREG3

Interactor 2: GBRL1 (Q9H0R8)
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Gene: GABARAPL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.50	0.660

Property	Details
Experiments	29892012, 25416956, 32296183, 26040720, unassigned1304
Identification Methods	two hybrid, pull down, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 466 Hs			1 117
+	Hs
		891208 RETR3_HUMAN (1-466): 0: 726: 100.00		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		306223 RETR3_HUMAN (1-466): 0: 726: 100.00		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		1202382 RETR3_HUMAN (1-466): 0: 726: 100.00		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		1202374 RETR3_HUMAN (1-466): 0: 726: 100.00		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		891323 RETR1_HUMAN (42-459): 0: 584: 36.82		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1328030 RETR1_HUMAN (42-459): 0: 584: 36.82		GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00
+	Hs
		306320 RETR1_HUMAN (42-459): 0: 584: 36.82		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Mm
		1257559 RETR1_MOUSE (8-459): 0: 600: 36.23		MLP3B_MOUSE (2-116): 3.03e-44: 141: 31.62
+	Hs
		1330625 RETR1_HUMAN (42-459): 0: 584: 36.82		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		1326146 RETR1_HUMAN (42-459): 0: 584: 36.82		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		61903 RETR1_HUMAN (42-459): 0: 584: 36.82		MP3B2_HUMAN (2-116): 6.71e-43: 138: 30.77
+	Hs
		1240861 RETR2_HUMAN (46-459): 1.23e-172: 497: 34.14		GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00
+	Hs
		306234 RETR2_HUMAN (46-459): 1.23e-172: 497: 34.14		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		1240862 RETR2_HUMAN (46-459): 1.23e-172: 497: 34.14		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		1240860 RETR2_HUMAN (46-459): 1.23e-172: 497: 34.14		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62