HitPredict

Interactor 1: HOOK3 (Q86VS8)
Protein Hook homolog 3 (h-hook3) (hHK3)
Gene: HOOK3

Interactor 2: SPAG5 (Q96R06)
Sperm-associated antigen 5 (Astrin) (Deepest) (Mitotic spindle-associated protein p126) (MAP126)
Gene: SPAG5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28718761
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0008017 - microtubule binding GO:0034451 - centriolar satellite GO:0071539 - protein localization to centrosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 718 Hs			1 1193
+	Hs
		318869 K2C75_HUMAN (277-608): 1.3e-30: 128: 15.32		SPAG5_HUMAN (1-1193): 4.62e-140: 457: 100.00
+	Hs
		1068588 HOOK3_HUMAN (1-718): 3.74e-57: 209: 100.00		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		725198 HOOK3_HUMAN (1-718): 3.74e-57: 209: 100.00		MYH10_HUMAN (837-1188): 2.71e-11: 70.7: 11.33
+	Hs
		528435 MYH8_HUMAN (289-718): 2.07e-17: 89.3: 10.27		MYH4_HUMAN (291-1062): 2.67e-30: 132: 12.19
+	Hs
		502933 MYH4_HUMAN (279-718): 3.71e-14: 78.7: 12.89		MYH3_HUMAN (173-1134): 9.39e-30: 131: 11.22
+	Hs
		528432 MYH8_HUMAN (289-718): 2.07e-17: 89.3: 10.27		MYH13_HUMAN (163-961): 2.75e-24: 113: 9.10
+	Rn
		361106 MYH6_RAT (349-718): 2.08e-13: 76.2: 11.97		MYH6_RAT (291-964): 6.07e-26: 118: 11.36
+	Hs
		522657 MYH4_HUMAN (279-718): 3.71e-14: 78.7: 12.89		MYH7_HUMAN (154-896): 6.03e-22: 105: 11.91
+	Hs
		1068595 K2C78_HUMAN (276-606): 5.85e-21: 99.3: 19.53		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		725097 MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71		MYH11_HUMAN (178-811): 8.64e-17: 88.4: 12.79
+	Hs
		1067423 EEA1_HUMAN (334-717): 7.89e-14: 77.7: 9.28		EEA1_HUMAN (691-1193): 8.44e-18: 91.8: 12.35
+	Hs
		725189 MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71		MYH14_HUMAN (449-1088): 6.07e-13: 75.8: 14.74
+	Hs
		725095 MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71		MYH10_HUMAN (837-1188): 2.71e-11: 70.7: 11.33
+	Hs
		724687 MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		1068696 HOOK1_HUMAN (196-712): 4.3e-14: 78.1: 12.98		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		148461 MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51
+	Hs
		148466 MYH11_HUMAN (308-712): 6.49e-15: 81.2: 8.94		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51
+	Hs
		149399 HOOK1_HUMAN (196-712): 4.3e-14: 78.1: 12.98		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51