HitPredict

Interactor 1: WDR5B (Q86VZ2)
WD repeat-containing protein 5B
Gene: WDR5B

Interactor 2: GRWD1 (Q9BQ67)
Glutamate-rich WD repeat-containing protein 1
Gene: GRWD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	17041588
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	CAF1C_H4-bd~WD40, WD40~WD40
Common GO terms	GO:0042393 - histone binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 330 Hs			1 446
+	Hs
		903471 WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21		GRWD1_HUMAN (1-446): 4.56e-121: 361: 100.00
+	Hs
		903077 WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21		WDR5_HUMAN (248-445): 8.04e-48: 168: 21.72
+	Dm
		1358845 WDS_DROME (2-286): 9.88e-95: 286: 29.90		WDS_DROME (248-445): 1.19e-46: 166: 21.21
+	Hs
		903418 FBXW7_HUMAN (1-319): 1.47e-88: 281: 28.40		WDR5_HUMAN (248-445): 8.04e-48: 168: 21.72
+	Hs
		792949 WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21		LIS1_HUMAN (243-445): 6.45e-42: 155: 17.00
+	Hs
		903171 WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21		RBBP4_HUMAN (62-247): 7.65e-20: 93.1: 10.71
+	Hs
		1083339 FBXW7_HUMAN (1-319): 1.47e-88: 281: 28.40		RBBP7_HUMAN (66-247): 3.57e-20: 94.3: 10.42
+	Hs
		903551 WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21		NLE1_HUMAN (338-445): 4.67e-18: 88.1: 13.89
+	Sp
		999838 TUP11_SCHPO (1-289): 8.64e-92: 287: 24.68		TUP11_SCHPO (62-182): 4.7e-15: 79.2: 7.97
+	Hs
		903349 WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21		WDR5B_HUMAN (348-445): 9.02e-15: 76.9: 16.33
+	Hs
		903313 WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21		WDR59_HUMAN (259-382): 1.24e-12: 72: 28.23
+	Hs
		1240442 POC1B_HUMAN (154-330): 5.19e-47: 166: 20.90		POC1A_HUMAN (208-445): 1.16e-53: 186: 15.97
+	Hs
		196984 PRP4_HUMAN (125-330): 6.22e-50: 175: 22.43		WDR5_HUMAN (248-445): 8.04e-48: 168: 21.72
+	Ce
		954090 LIS1_CAEEL (2-240): 7.23e-73: 232: 27.06		LIN53_CAEEL (41-247): 1.86e-21: 97.7: 10.33
+	Hs
		209416 PLRG1_HUMAN (158-328): 2.42e-40: 149: 28.66		WDR5_HUMAN (248-445): 8.04e-48: 168: 21.72
+	Hs
		1309163 TBL1Y_HUMAN (62-330): 1.59e-59: 200: 24.40		TBL1R_HUMAN (94-292): 5.97e-27: 115: 14.08
+	Hs
		245633 TBL1X_HUMAN (120-330): 1.23e-48: 173: 27.56		TBL1R_HUMAN (94-292): 5.97e-27: 115: 14.08
+	Hs
		245613 TBL1X_HUMAN (120-330): 1.23e-48: 173: 27.56		WDR59_HUMAN (259-382): 1.24e-12: 72: 28.23
+	Hs
		1162302 TBL1R_HUMAN (120-330): 3.57e-48: 170: 28.00		WDR59_HUMAN (259-382): 1.24e-12: 72: 28.23