Interactor 1: THOC6 (Q86W42)
THO complex subunit 6 homolog (Functional spliceosome-associated protein 35) (fSAP35) (WD repeat-containing protein 58)
Gene: THOC6

Interactor 2: THOC3 (Q96J01)
THO complex subunit 3 (Tho3) (TEX1 homolog) (hTREX45)
Gene: THOC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC4_WD40~WD40
Common GO terms GO:0000346 - transcription export complex
GO:0000445 - THO complex part of transcription export complex
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0006397 - mRNA processing
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 341
Hs

1 351
+ Dm
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ Sp
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Mm
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024