HitPredict

Interactor 1: RHOD (O00212)
Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1)
Gene: RHOD

Interactor 2: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 210 Hs			1 745
+	Hs
		542450 RHOF_HUMAN (7-193): 1.18e-78: 236: 54.26		PLAK_HUMAN (1-745): 0: 551: 100.00
+	Hs
		542271 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		PLAK_HUMAN (1-745): 0: 551: 100.00
+	Hs
		542173 RHOQ_HUMAN (12-210): 7.44e-74: 223: 42.08		PLAK_HUMAN (1-745): 0: 551: 100.00
+	Hs
		542254 RAC3_HUMAN (15-191): 1.93e-73: 222: 51.98		PLAK_HUMAN (1-745): 0: 551: 100.00
+	Hs
		717355 RHOF_HUMAN (7-193): 1.18e-78: 236: 54.26		CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38
+	Hs
		120321 RHOD_HUMAN (1-210): 1.91e-77: 232: 100.00		CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38
+	Hs
		716971 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38
+	Mm
		925786 RAC1_MOUSE (15-202): 3.58e-77: 231: 50.00		CTNB1_MOUSE (1-731): 2.79e-173: 518: 67.38
+	Hs
		564428 RHOQ_HUMAN (12-210): 7.44e-74: 223: 42.08		CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38
+	Hs
		716929 RAC3_HUMAN (15-191): 1.93e-73: 222: 51.98		CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38
+	Hs
		120234 RHOD_HUMAN (1-210): 1.91e-77: 232: 100.00		CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25
+	Hs
		239111 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25
+	Hs
		239045 RHOQ_HUMAN (12-210): 7.44e-74: 223: 42.08		CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25
+	Hs
		239040 RAC2_HUMAN (15-209): 1.06e-73: 222: 45.64		CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25
+	Hs
		134868 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		IMA3_HUMAN (228-670): 2.7e-65: 227: 16.01
+	Hs
		853717 RHOF_HUMAN (7-193): 1.18e-78: 236: 54.26		IMA5_HUMAN (231-685): 6.58e-61: 215: 15.06
+	Hs
		853562 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		IMA5_HUMAN (231-685): 6.58e-61: 215: 15.06
+	Hs
		853234 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		IMA1_HUMAN (270-664): 6.19e-48: 179: 14.32
+	Hs
		238654 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		IMA7_HUMAN (262-685): 3.97e-45: 172: 13.86
+	Hs
		119785 RHOF_HUMAN (7-193): 1.18e-78: 236: 54.26		ARVC_HUMAN (203-647): 2.38e-15: 82.5: 18.54