HitPredict

Interactor 1: TRI69 (Q86WT6)
E3 ubiquitin-protein ligase TRIM69 (EC 2.3.2.27) (RFP-like domain-containing protein trimless) (RING finger protein 36) (RING-type E3 ubiquitin transferase TRIM69) (Tripartite motif-containing protein 69)
Gene: TRIM69

Interactor 2: TRIM4 (Q9C037)
E3 ubiquitin-protein ligase TRIM4 (EC 2.3.2.27) (RING finger protein 87) (RING-type E3 ubiquitin transferase TRIM4) (Tripartite motif-containing protein 4)
Gene: TRIM4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PRY~SPRY, SPRY~SPRY, zf-C3HC4_4~zf-C3HC4_4
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0061630 - ubiquitin protein ligase activity
Homologous interactions 16

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024