Interactor 1: STING (Q86WV6)
Stimulator of interferon genes protein (hSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (hMITA) (Transmembrane protein 173)
Gene: STING1

Interactor 2: IRF7 (Q92985)
Interferon regulatory factor 7 (IRF-7)
Gene: IRF7

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 18818105
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0032481 - positive regulation of type I interferon production
GO:0032728 - positive regulation of interferon-beta production
and 4 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 379
Hs

1 503
+ Mm
+ Hs

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Last updated: 15 Jul 2024