Interactor 1: STING (Q86WV6)
Stimulator of interferon genes protein (hSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (hMITA) (Transmembrane protein 173)
Gene: STING1

Interactor 2: TRI56 (Q9BRZ2)
E3 ubiquitin-protein ligase TRIM56 (EC 2.3.2.27) (RING finger protein 109) (Tripartite motif-containing protein 56)
Gene: TRIM56

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.640

The method score is based on:

Property Details
Experiments 35281267, 21074459, 25505063
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0032728 - positive regulation of interferon-beta production
GO:0045087 - innate immune response
GO:0051607 - defense response to virus
GO:0060340 - positive regulation of type I interferon-mediated signaling pathway
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 379
Hs

1 755
+ Mm
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024