Interactor 1: STING (Q86WV6)
Stimulator of interferon genes protein (hSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (hMITA) (Transmembrane protein 173)
Gene: STING1
Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 0.60 | 0.767 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32383759, 33767426, 35909127, 37130168, 21074459, 22745133, 28763789, 28346439, 29899553, 30943264, 31534043, 33086059, 33139700, 32678307, 35107381, 33723219, 36755358, 35765167, 36972172, 21903422 and 8 others
more... |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002218 - activation of innate immune response GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016239 - positive regulation of macroautophagy and 9 others more... |
| Homologous interactions | 7 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
