HitPredict

Interactor 1: RHOD (O00212)
Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1)
Gene: RHOD

Interactor 2: DSC2 (Q02487)
Desmocollin-2 (Cadherin family member 2) (Desmocollin-3) (Desmosomal glycoprotein II) (Desmosomal glycoprotein III)
Gene: DSC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 210 Hs			1 901
+	Hs
		971067 RHOF_HUMAN (7-193): 1.18e-78: 236: 54.26		DSC2_HUMAN (1-901): 0: 855: 100.00
+	Hs
		925210 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		DSC2_HUMAN (1-901): 0: 855: 100.00
+	Hs
		564486 RHOQ_HUMAN (12-210): 7.44e-74: 223: 42.08		DSC2_HUMAN (1-901): 0: 855: 100.00
+	Hs
		545331 RAC2_HUMAN (15-209): 1.06e-73: 222: 45.64		DSC2_HUMAN (1-901): 0: 855: 100.00
+	Hs
		892326 RAC3_HUMAN (15-191): 1.93e-73: 222: 51.98		DSC2_HUMAN (1-901): 0: 855: 100.00
+	Hs
		971065 RHOJ_HUMAN (3-209): 1.65e-72: 220: 38.65		DSC2_HUMAN (1-901): 0: 855: 100.00
+	Hs
		1055857 RHOF_HUMAN (7-193): 1.18e-78: 236: 54.26		DSC3_HUMAN (1-901): 0: 806: 66.70
+	Hs
		564530 RHOQ_HUMAN (12-210): 7.44e-74: 223: 42.08		DSC3_HUMAN (1-901): 0: 806: 66.70
+	Hs
		120300 RHOD_HUMAN (1-210): 1.91e-77: 232: 100.00		CADH2_HUMAN (4-385): 1.04e-51: 197: 15.55
+	Hs
		580220 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		CADH2_HUMAN (4-385): 1.04e-51: 197: 15.55
+	Hs
		545200 RAC2_HUMAN (15-209): 1.06e-73: 222: 45.64		CADH2_HUMAN (4-385): 1.04e-51: 197: 15.55
+	Hs
		580218 RAC3_HUMAN (15-191): 1.93e-73: 222: 51.98		CADH2_HUMAN (4-385): 1.04e-51: 197: 15.55
+	Hs
		580261 RHOJ_HUMAN (3-209): 1.65e-72: 220: 38.65		CADH2_HUMAN (4-385): 1.04e-51: 197: 15.55
+	Hs
		925399 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		DSG4_HUMAN (20-372): 1.22e-32: 138: 17.84
+	Hs
		1048669 RHOF_HUMAN (7-193): 1.18e-78: 236: 54.26		DSG2_HUMAN (69-401): 2e-20: 99.3: 17.18
+	Hs
		120431 RHOD_HUMAN (1-210): 1.91e-77: 232: 100.00		DSG2_HUMAN (69-401): 2e-20: 99.3: 17.18
+	Hs
		925270 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		DSG2_HUMAN (69-401): 2e-20: 99.3: 17.18
+	Hs
		564523 RHOQ_HUMAN (12-210): 7.44e-74: 223: 42.08		DSG2_HUMAN (69-401): 2e-20: 99.3: 17.18
+	Hs
		545367 RAC2_HUMAN (15-209): 1.06e-73: 222: 45.64		DSG2_HUMAN (69-401): 2e-20: 99.3: 17.18
+	Hs
		892364 RAC3_HUMAN (15-191): 1.93e-73: 222: 51.98		DSG2_HUMAN (69-401): 2e-20: 99.3: 17.18