Interactor 1: TCAM2 (Q86XR7)
TIR domain-containing adapter molecule 2 (TICAM-2) (Putative NF-kappa-B-activating protein 502) (TRIF-related adapter molecule) (Toll-like receptor adaptor protein 3) (Toll/interleukin-1 receptor domain-containing protein) (MyD88-4)
Gene: TICAM2

Interactor 2: TCAM2 (Q86XR7)
TIR domain-containing adapter molecule 2 (TICAM-2) (Putative NF-kappa-B-activating protein 502) (TRIF-related adapter molecule) (Toll-like receptor adaptor protein 3) (Toll/interleukin-1 receptor domain-containing protein) (MyD88-4)
Gene: TICAM2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 1.00 0.730

The method score is based on:

Property Details
Experiments 24255114, 17258210
Identification Methods two hybrid, mammalian protein protein interaction trap
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TIR_2~TIR_2
Common GO terms GO:0001891 - phagocytic cup
GO:0002735 - positive regulation of myeloid dendritic cell cytokine production
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005770 - late endosome
and 28 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 235
Hs

1 235
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024