Interactor 1: TCAM2 (Q86XR7)
TIR domain-containing adapter molecule 2 (TICAM-2) (Putative NF-kappa-B-activating protein 502) (TRIF-related adapter molecule) (Toll-like receptor adaptor protein 3) (Toll/interleukin-1 receptor domain-containing protein) (MyD88-4)
Gene: TICAM2

Interactor 2: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24265315
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TIR_2~TIR_2
Common GO terms GO:0005886 - plasma membrane
GO:0006909 - phagocytosis
GO:0010008 - endosome membrane
GO:0031663 - lipopolysaccharide-mediated signaling pathway
GO:0032481 - positive regulation of type I interferon production
and 6 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 235
Hs

1 296
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Last updated: 15 Jul 2024