HitPredict

Interactor 1: GOLI (Q86XS8)
E3 ubiquitin-protein ligase RNF130 (EC 2.3.2.27) (Goliath homolog) (H-Goliath) (RING finger protein 130) (RING-type E3 ubiquitin transferase RNF130)
Gene: RNF130

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36610398
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_2
Common GO terms	GO:0005737 - cytoplasm GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 419 Hs			1 624
+	Hs
		1204865 GOLI_HUMAN (1-419): 4.48e-123: 365: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		1204844 GOLI_HUMAN (1-419): 4.48e-123: 365: 100.00		UBQL4_HUMAN (22-624): 2.17e-124: 382: 54.55
+	Hs
		1255992 RN128_HUMAN (1-384): 4.57e-89: 278: 36.90		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		1240835 RN149_HUMAN (25-343): 1.03e-80: 255: 41.85		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		924340 GOLI_HUMAN (1-419): 4.48e-123: 365: 100.00		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		924057 GOLI_HUMAN (1-419): 4.48e-123: 365: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		803648 RN149_HUMAN (25-343): 1.03e-80: 255: 41.85		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		803617 SYVN1_HUMAN (17-312): 1.08e-56: 198: 14.38		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		803801 AMFR_HUMAN (2-346): 7.99e-45: 166: 13.50		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Dm
		1362823 GZL_DROME (16-415): 1.37e-64: 217: 19.90		Q9VCD5_DROME (33-258): 3.37e-32: 127: 15.58
+	Hs
		924365 ZNRF4_HUMAN (6-375): 3.81e-59: 200: 18.95		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		924212 AMFR_HUMAN (2-346): 7.99e-45: 166: 13.50		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		803773 RNF12_HUMAN (210-311): 1.31e-10: 65.1: 33.33		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		803824 RN115_HUMAN (237-305): 5.8e-11: 65.1: 44.93		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23