HitPredict

Interactor 1: DTX1 (Q86Y01)
E3 ubiquitin-protein ligase DTX1 (EC 2.3.2.27) (Protein deltex-1) (Deltex1) (hDTX1) (RING-type E3 ubiquitin transferase DTX1)
Gene: DTX1

Interactor 2: DTX1 (Q86Y01)
E3 ubiquitin-protein ligase DTX1 (EC 2.3.2.27) (Protein deltex-1) (Deltex1) (hDTX1) (RING-type E3 ubiquitin transferase DTX1)
Gene: DTX1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.840

The method score is based on:

Property Details
Experiments 29440432, 11564735, 32948590
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DTC~DTC, DTC~zf-C3HC4, WWE~WWE
Common GO terms GO:0003713 - transcription coactivator activity
GO:0005112 - Notch binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 16 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 620
Hs

1 620
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024