HitPredict

Interactor 1: RHOD (O00212)
Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1)
Gene: RHOD

Interactor 2: CYFP1 (Q7L576)
Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1)
Gene: CYFIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030032 - lamellipodium assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 210 Hs			1 1253
+	Hs
		1184658 RHOF_HUMAN (7-193): 1.18e-78: 236: 54.26		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		925386 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Mm
		925800 RAC1_MOUSE (15-202): 3.58e-77: 231: 50.00		CYFP1_MOUSE (1-1253): 0: 2079: 99.04
+	Hs
		545463 RAC2_HUMAN (15-209): 1.06e-73: 222: 45.64		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		892449 RAC3_HUMAN (15-191): 1.93e-73: 222: 51.98		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		1184655 RHOJ_HUMAN (3-209): 1.65e-72: 220: 38.65		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		900624 RHOA_HUMAN (19-206): 5.15e-73: 220: 51.06		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		951104 RHOG_HUMAN (15-202): 1.14e-72: 220: 44.68		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		894162 CDC42_HUMAN (15-202): 4.43e-72: 218: 44.68		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		925513 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		545555 RAC2_HUMAN (15-209): 1.06e-73: 222: 45.64		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		892535 RAC3_HUMAN (15-191): 1.93e-73: 222: 51.98		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		900789 RHOA_HUMAN (19-206): 5.15e-73: 220: 51.06		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		951231 RHOG_HUMAN (15-202): 1.14e-72: 220: 44.68		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		915782 RHOB_HUMAN (19-194): 3.61e-66: 203: 53.98		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Mm
		1143609 RHOC_MOUSE (19-201): 9.23e-68: 207: 52.46		CYFP1_MOUSE (1-1253): 0: 2079: 99.04
+	Dm
		776913 RAC1_DROME (15-202): 4.22e-74: 223: 48.94		CYFIP_DROME (1-1253): 0: 1903: 65.73
+	At
		1105104 RAC1_ARATH (13-191): 5.04e-89: 261: 44.13		PIR_ARATH (5-1240): 0: 1535: 28.88
+	At
		1105163 RAC5_ARATH (13-191): 6e-89: 261: 43.58		PIR_ARATH (5-1240): 0: 1535: 28.88
+	At
		1105123 RAC3_ARATH (13-194): 7.6e-83: 246: 44.51		PIR_ARATH (5-1240): 0: 1535: 28.88