HitPredict

Interactor 1: LRC33 (Q86YC3)
Transforming growth factor beta activator LRRC33 (Leucine-rich repeat-containing protein 33) (Negative regulator of reactive oxygen species)
Gene: NRROS

Interactor 2: CNPY3 (Q9BT09)
Protein canopy homolog 3 (CTG repeat protein 4a) (Expanded repeat-domain protein CAG/CTG 5) (Protein associated with TLR4) (Trinucleotide repeat-containing gene 5 protein)
Gene: CNPY3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	28514442, 33961781, 36966971
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 692 Hs			1 278
+	Hs
		265897 LGR5_HUMAN (185-582): 3.04e-38: 154: 22.73		CNPY3_HUMAN (1-278): 9.66e-149: 419: 100.00
+	Hs
		1294954 LRIG1_HUMAN (331-653): 3.39e-32: 136: 20.39		CNPY3_HUMAN (1-278): 9.66e-149: 419: 100.00
+	Hs
		728889 ALS_HUMAN (335-613): 1.88e-23: 107: 24.82		CNPY3_HUMAN (1-278): 9.66e-149: 419: 100.00
+	Hs
		1053494 LRC32_HUMAN (376-691): 4.67e-20: 96.7: 20.06		CNPY3_HUMAN (1-278): 9.66e-149: 419: 100.00
+	Hs
		1291077 LIGO1_HUMAN (58-241): 1.5e-19: 95.2: 19.21		CNPY3_HUMAN (1-278): 9.66e-149: 419: 100.00
+	Hs
		237437 TLR5_HUMAN (134-472): 2.94e-16: 85.1: 29.61		CNPY3_HUMAN (1-278): 9.66e-149: 419: 100.00
+	Hs
		1185469 LIGO2_HUMAN (34-389): 7.81e-14: 77: 24.65		CNPY3_HUMAN (1-278): 9.66e-149: 419: 100.00
+	Hs
		770238 GPV_HUMAN (60-391): 5.17e-12: 70.9: 28.66		CNPY3_HUMAN (1-278): 9.66e-149: 419: 100.00
+	Hs
		1311700 TLR9_HUMAN (48-177): 2.19e-10: 66.3: 25.39		CNPY3_HUMAN (1-278): 9.66e-149: 419: 100.00
+	Hs
		299582 LRIG2_HUMAN (134-495): 5.25e-09: 61.6: 25.27		CNPY3_HUMAN (1-278): 9.66e-149: 419: 100.00
+	Hs
		1311701 TLR8_HUMAN (58-405): 8.63e-09: 60.8: 26.49		CNPY3_HUMAN (1-278): 9.66e-149: 419: 100.00
+	Hs
		1230128 LGR4_HUMAN (331-614): 1.56e-37: 152: 24.21		CNPY4_HUMAN (17-215): 2.14e-110: 320: 48.00
+	Hs
		1191118 PODN_HUMAN (185-676): 6.66e-35: 142: 22.59		CNPY4_HUMAN (17-215): 2.14e-110: 320: 48.00
+	Hs
		1230126 LRIG1_HUMAN (331-653): 3.39e-32: 136: 20.39		CNPY4_HUMAN (17-215): 2.14e-110: 320: 48.00
+	Hs
		770229 GPV_HUMAN (60-391): 5.17e-12: 70.9: 28.66		CNPY4_HUMAN (17-215): 2.14e-110: 320: 48.00