HitPredict

Interactor 1: HOME1 (Q86YM7)
Homer protein homolog 1 (Homer-1)
Gene: HOMER1

Interactor 2: DBNL (Q9UJU6)
Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F) (HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7)
Gene: DBNL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	22043307
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0030425 - dendrite and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 354 Hs			1 430
+	Hs
		1084993 HOME1_HUMAN (1-354): 4.46e-62: 204: 100.00		DREB_HUMAN (3-379): 1.4e-59: 207: 29.19
+	Hs
		1085077 HOME3_HUMAN (3-354): 3.77e-60: 199: 49.72		DREB_HUMAN (3-379): 1.4e-59: 207: 29.19
+	Hs
		1085076 HOME2_HUMAN (1-351): 8.57e-56: 187: 51.00		DREB_HUMAN (3-379): 1.4e-59: 207: 29.19
+	Hs
		787923 EPS15_HUMAN (92-321): 5.03e-30: 123: 11.97		DREB_HUMAN (3-379): 1.4e-59: 207: 29.19
+	Rn
		1376731 HOME1_RAT (1-354): 5.84e-58: 193: 94.26		SHAN1_RAT (100-429): 7.75e-34: 136: 13.82
+	Mm
		88379 HOME1_MOUSE (1-354): 2.36e-58: 194: 95.36		SHAN1_MOUSE (100-429): 2.53e-33: 135: 13.82
+	Mm
		88374 HOME3_MOUSE (3-354): 1.54e-57: 192: 47.44		SHAN1_MOUSE (100-429): 2.53e-33: 135: 13.82
+	Hs
		840483 VASP_HUMAN (1-146): 3.19e-28: 115: 22.36		DREB_HUMAN (3-379): 1.4e-59: 207: 29.19
+	Hs
		1025404 CACO2_HUMAN (116-340): 1.19e-25: 108: 17.70		DREB_HUMAN (3-379): 1.4e-59: 207: 29.19
+	Hs
		840566 VASP_HUMAN (1-146): 3.19e-28: 115: 22.36		SH3G1_HUMAN (166-429): 2.58e-35: 135: 17.74
+	Hs
		61732 EPS15_HUMAN (92-321): 5.03e-30: 123: 11.97		A6H8W8_HUMAN (70-428): 7.79e-15: 78.9: 10.65
+	Hs
		787985 EPS15_HUMAN (92-321): 5.03e-30: 123: 11.97		ITSN2_HUMAN (79-428): 1.09e-14: 78.5: 9.41
+	Mm
		936832 VASP_MOUSE (1-146): 6.58e-31: 122: 21.66		LASP1_MOUSE (209-429): 1.08e-15: 78.5: 18.47
+	Hs
		840475 VASP_HUMAN (1-146): 3.19e-28: 115: 22.36		LASP1_HUMAN (246-429): 2.85e-15: 77.3: 24.24
+	Hs
		787920 EPS15_HUMAN (92-321): 5.03e-30: 123: 11.97		ITSN1_HUMAN (277-429): 8.12e-10: 63.1: 17.83
+	Hs
		235499 CACO2_HUMAN (116-340): 1.19e-25: 108: 17.70		VINEX_HUMAN (283-429): 1.82e-14: 77.4: 18.67
+	Cl
		47357 A0A8I3PJA6_CANLF (65-335): 2.13e-29: 121: 11.81		F1PHV6_CANLF (277-429): 3.63e-09: 61.2: 17.83
+	Rn
		92844 E9PSY8_RAT (65-332): 5.16e-28: 117: 12.69		ITSN1_RAT (279-429): 5.77e-10: 63.5: 16.77
+	Mm
		788010 EPS15_MOUSE (65-332): 1.05e-27: 116: 13.06		ITSN1_MOUSE (279-429): 1.82e-09: 62: 18.07
+	Hs
		61738 EP15R_HUMAN (65-303): 4.1e-18: 87.8: 11.94		A6H8W8_HUMAN (70-428): 7.79e-15: 78.9: 10.65