HitPredict

Interactor 1: P66A (Q86YP4)
Transcriptional repressor p66-alpha (Hp66alpha) (GATA zinc finger domain-containing protein 2A)
Gene: GATAD2A

Interactor 2: MB3L1 (Q8WWY6)
Methyl-CpG-binding domain protein 3-like 1 (MBD3-like protein 1)
Gene: MBD3L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.926

Property	Details
Experiments	32296183, 26186194, 28514442, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	MBD_C~P66_CC
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 633 Hs			1 194
+	Hs
		328592 P66A_HUMAN (1-633): 0: 836: 100.00		MBD3_HUMAN (1-193): 3.4e-102: 297: 44.56
+	Hs
		1205828 P66A_HUMAN (1-633): 0: 836: 100.00		MBD2_HUMAN (1-182): 5.61e-85: 258: 41.76
+	Hs
		1205779 P66A_HUMAN (1-633): 0: 836: 100.00		MB3L2_HUMAN (26-187): 5.81e-61: 190: 45.73
+	Hs
		328620 P66B_HUMAN (1-631): 0: 627: 39.79		MBD3_HUMAN (1-193): 3.4e-102: 297: 44.56
+	Hs
		1263068 P66B_HUMAN (1-631): 0: 627: 39.79		MB3L1_HUMAN (1-194): 1.26e-98: 285: 100.00
+	Hs
		1263987 P66B_HUMAN (1-631): 0: 627: 39.79		MBD2_HUMAN (1-182): 5.61e-85: 258: 41.76
+	Hs
		1246254 P66B_HUMAN (1-631): 0: 627: 39.79		MB3L2_HUMAN (26-187): 5.81e-61: 190: 45.73