HitPredict

Interactor 1: Q8AW91 (Q8AW91)
Structural maintenance of chromosomes protein
Gene: smc3.L

Interactor 2: STAG2 (Q9DGN0)
Cohesin subunit SA-2 (xSA-2) (SCC3 homolog 2) (Stromal antigen 2 homolog)
Gene: STAG2

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	10931856, 15855230
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1217 Xl			1 1194
+	Xl
		1140122 Q8AW91_XENLA (1-1217): 5.12e-130: 430: 100.00		Q5XGV2_XENLA (1-1194): 0: 1644: 97.82
+	Xl
		292741 SMC3_XENLA (1-1217): 3.66e-127: 422: 99.18		STAG2_XENLA (1-1194): 0: 1634: 100.00
+	Mm
		193224 SMC3_MOUSE (1-1217): 2.26e-127: 423: 96.80		STAG2_MOUSE (1-1194): 0: 1574: 88.50
+	Hs
		1232591 SMC3_HUMAN (1-1217): 3.79e-127: 422: 96.71		STAG2_HUMAN (1-1194): 0: 1572: 88.42
+	Hs
		1261592 SMC3_HUMAN (1-1217): 3.79e-127: 422: 96.71		STAG1_HUMAN (2-1194): 0: 1553: 71.19
+	Xl
		292742 SMC3_XENLA (1-1217): 3.66e-127: 422: 99.18		STAG1_XENLA (2-1194): 0: 1526: 70.39
+	Xl
		292732 SMC1A_XENLA (2-1211): 3.35e-74: 271: 15.56		Q5XGV2_XENLA (1-1194): 0: 1644: 97.82
+	Xl
		292734 SMC1A_XENLA (2-1211): 3.35e-74: 271: 15.56		STAG2_XENLA (1-1194): 0: 1634: 100.00
+	Mm
		193223 SMC1A_MOUSE (2-1211): 2.26e-79: 287: 15.88		STAG2_MOUSE (1-1194): 0: 1574: 88.50
+	Hs
		1057313 SMC1A_HUMAN (2-1211): 3.37e-79: 286: 15.88		STAG2_HUMAN (1-1194): 0: 1572: 88.42
+	Hs
		1057335 SMC1A_HUMAN (2-1211): 3.37e-79: 286: 15.88		STAG1_HUMAN (2-1194): 0: 1553: 71.19
+	Xl
		292735 SMC1A_XENLA (2-1211): 3.35e-74: 271: 15.56		STAG1_XENLA (2-1194): 0: 1526: 70.39
+	Hs
		1355962 SMC3_HUMAN (1-1217): 3.79e-127: 422: 96.71		STAG3_HUMAN (4-1094): 0: 1298: 51.41
+	Mm
		251067 SMC3_MOUSE (1-1217): 2.26e-127: 423: 96.80		STAG3_MOUSE (2-1094): 0: 1213: 50.32
+	Hs
		1057419 SMC1A_HUMAN (2-1211): 3.37e-79: 286: 15.88		STAG3_HUMAN (4-1094): 0: 1298: 51.41
+	Sp
		143294 SMC3_SCHPO (1-1212): 3.62e-90: 318: 39.03		SCC3_SCHPO (8-674): 0: 593: 21.56
+	Sp
		143296 SMC1_SCHPO (2-1204): 7.59e-71: 261: 15.36		SCC3_SCHPO (8-674): 0: 593: 21.56
+	Sp
		193879 SMC3_SCHPO (1-1212): 3.62e-90: 318: 39.03		REC11_SCHPO (12-639): 2.77e-150: 476: 15.58
+	Sp
		293287 SMC1_SCHPO (2-1204): 7.59e-71: 261: 15.36		REC11_SCHPO (12-639): 2.77e-150: 476: 15.58
+	Sc
		775340 SMC3_YEAST (1-1217): 4.95e-85: 304: 29.88		SCC3_YEAST (8-350): 7.1e-79: 284: 25.00