Interactor 1: ERLN2 (Q8BFZ9)
Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2)
Gene: Erlin2

Interactor 2: ERLN1 (Q91X78)
Erlin-1 (Endoplasmic reticulum lipid raft-associated protein 1) (Protein KE04 homolog) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1) (SPFH domain-containing protein 1)
Gene: Erlin1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 30135210
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Band_7~Band_7
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0008203 - cholesterol metabolic process
GO:0015485 - cholesterol binding
GO:0031625 - ubiquitin protein ligase binding
GO:0032933 - SREBP signaling pathway
and 4 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 340
Mm

1 348
+ Rn
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Dm
+ Mm
+ Hs
+ Ss
+ Mm
+ Hs

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Last updated: 15 Jul 2024