HitPredict

Interactor 1: RHOD (O00212)
Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1)
Gene: RHOD

Interactor 2: BORG4 (Q9H3Q1)
Cdc42 effector protein 4 (Binder of Rho GTPases 4)
Gene: CDC42EP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PBD~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007266 - Rho protein signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 210 Hs			1 356
+	Hs
		1330289 RHOF_HUMAN (7-193): 1.18e-78: 236: 54.26		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		925610 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		564682 RHOQ_HUMAN (12-210): 7.44e-74: 223: 42.08		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		545611 RAC2_HUMAN (15-209): 1.06e-73: 222: 45.64		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		892591 RAC3_HUMAN (15-191): 1.93e-73: 222: 51.98		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		1330288 RHOJ_HUMAN (3-209): 1.65e-72: 220: 38.65		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		900891 RHOA_HUMAN (19-206): 5.15e-73: 220: 51.06		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		951333 RHOG_HUMAN (15-202): 1.14e-72: 220: 44.68		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		960662 RHOF_HUMAN (7-193): 1.18e-78: 236: 54.26		BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16
+	Hs
		120391 RHOD_HUMAN (1-210): 1.91e-77: 232: 100.00		BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16
+	Hs
		925198 RAC1_HUMAN (15-202): 3.58e-77: 231: 50.00		BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16
+	Hs
		564729 RHOQ_HUMAN (12-210): 7.44e-74: 223: 42.08		BORG2_HUMAN (2-229): 1.35e-56: 186: 24.21
+	Hs
		564481 RHOQ_HUMAN (12-210): 7.44e-74: 223: 42.08		BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16
+	Hs
		545325 RAC2_HUMAN (15-209): 1.06e-73: 222: 45.64		BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16
+	Hs
		892320 RAC3_HUMAN (15-191): 1.93e-73: 222: 51.98		BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16
+	Hs
		900382 RHOA_HUMAN (19-206): 5.15e-73: 220: 51.06		BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16
+	Hs
		950927 RHOG_HUMAN (15-202): 1.14e-72: 220: 44.68		BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16
+	Hs
		960657 RHOJ_HUMAN (3-209): 1.65e-72: 220: 38.65		BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16
+	Hs
		150121 RHOQ_HUMAN (12-210): 7.44e-74: 223: 42.08		BORG1_HUMAN (1-228): 1.31e-47: 162: 25.86
+	Hs
		150124 CDC42_HUMAN (15-202): 4.43e-72: 218: 44.68		BORG1_HUMAN (1-228): 1.31e-47: 162: 25.86