HitPredict

Interactor 1: DLGP2 (Q8BJ42)
Disks large-associated protein 2 (DAP-2) (PSD-95/SAP90-binding protein 2) (SAP90/PSD-95-associated protein 2) (SAPAP2)
Gene: Dlgap2

Interactor 2: DLGP1 (Q9D415)
Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1)
Gene: Dlgap1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	27507650, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GKAP~GKAP
Common GO terms	GO:0019904 - protein domain specific binding GO:0050804 - modulation of chemical synaptic transmission GO:0060090 - molecular adaptor activity GO:0098978 - glutamatergic synapse GO:0099092 - postsynaptic density, intracellular component and 1 others more... GO:0099572 - postsynaptic specialization
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1059 Mm			1 992
+	Rn
		956986 DLGP2_RAT (1-1059): 0: 1544: 97.55		DLGP1_RAT (1-992): 0: 1344: 98.49
+	Hs
		1349918 DLGP2_HUMAN (1-1059): 0: 1526: 89.14		DLGP4_HUMAN (1-992): 0: 1071: 46.37
+	Hs
		4620 A0A1B0GTN4_HUMAN (5-1059): 0: 1516: 89.01		DLGP4_HUMAN (1-992): 0: 1071: 46.37
+	Mm
		69922 DLGP1_MOUSE (80-1059): 0: 1171: 50.53		DLGP4_MOUSE (1-992): 0: 1056: 45.88
+	Mm
		1161317 DLGP1_MOUSE (80-1059): 0: 1171: 50.53		DLGP3_MOUSE (1-992): 0: 978: 38.13
+	Mm
		1225304 DLGP1_MOUSE (80-1059): 0: 1171: 50.53		DLGP5_MOUSE (533-977): 4.63e-100: 334: 17.46