Interactor 1: SIN1 (Q8BKH7)
Target of rapamycin complex 2 subunit MAPKAP1 (TORC2 subunit MAPKAP1) (Mitogen-activated protein kinase 2-associated protein 1) (Stress-activated map kinase-interacting protein 1) (SAPK-interacting protein 1)
Gene: Mapkap1

Interactor 2: MTOR (Q9JLN9)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1)
Gene: MTOR

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.919

The method score is based on:

Property Details
Experiments 18566586, 18851840, 27340174, 18505677, 21045808
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CRIM~FRB_dom, CRIM~PI3_PI4_kinase
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007010 - cytoskeleton organization
GO:0019901 - protein kinase binding
GO:0030307 - positive regulation of cell growth
and 4 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 522
Mm

1 2549
+ Hs
+ Dm
+ Sp
+ Sp
+ Hs

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Last updated: 15 Jul 2024