HitPredict

Interactor 1: Q8BPK8 (Q8BPK8)
Agenet-like domain-containing protein
Gene: Fmr1

Interactor 2: AGO2 (Q8CJG0)
Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer)
Gene: AGO2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0016020 - membrane GO:0036464 - cytoplasmic ribonucleoprotein granule GO:0043488 - regulation of mRNA stability GO:0045727 - positive regulation of translation
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 357 Mm			1 860
+	Mm
		729560 FMR1_MOUSE (1-357): 0: 654: 100.00		AGO2_MOUSE (1-860): 0: 1216: 100.00
+	Hs
		989178 FMR1_HUMAN (1-357): 0: 649: 97.76		AGO2_HUMAN (21-860): 0: 1193: 99.88
+	Mm
		729561 FMR1_MOUSE (1-357): 0: 654: 100.00		AGO1_MOUSE (18-860): 0: 1173: 83.16
+	Mm
		1207064 Q8BPK8_MOUSE (1-357): 0: 650: 100.00		AGO1_MOUSE (18-860): 0: 1173: 83.16
+	Hs
		989179 FMR1_HUMAN (1-357): 0: 649: 97.76		AGO1_HUMAN (18-860): 0: 1173: 83.16
+	Mm
		1142880 FXR1_MOUSE (1-334): 0: 589: 73.65		AGO2_MOUSE (1-860): 0: 1216: 100.00
+	Mm
		1110532 Q3TA75_MOUSE (4-334): 0: 575: 71.30		AGO2_MOUSE (1-860): 0: 1216: 100.00
+	Hs
		843956 FXR1_HUMAN (1-334): 0: 592: 73.95		AGO2_HUMAN (21-860): 0: 1193: 99.88
+	Hs
		844280 FXR2_HUMAN (4-334): 0: 579: 71.90		AGO2_HUMAN (21-860): 0: 1193: 99.88
+	Hs
		843957 FXR1_HUMAN (1-334): 0: 592: 73.95		AGO1_HUMAN (18-860): 0: 1173: 83.16
+	Mm
		1142881 FXR1_MOUSE (1-334): 0: 589: 73.65		AGO1_MOUSE (18-860): 0: 1173: 83.16
+	Hs
		844281 FXR2_HUMAN (4-334): 0: 579: 71.90		AGO1_HUMAN (18-860): 0: 1173: 83.16
+	Hs
		844248 FXR2_HUMAN (4-334): 0: 579: 71.90		AGO3_HUMAN (17-860): 0: 1155: 80.07
+	Dm
		1103827 FMR1_DROME (1-334): 6.97e-178: 511: 45.93		Q32KD4_DROME (4-860): 0: 1129: 72.97
+	Dm
		1342058 FMR1_DROME (1-334): 6.97e-178: 511: 45.93		AGO2_DROME (31-819): 0: 713: 30.84
+	Dm
		1342050 FMR1_DROME (1-334): 6.97e-178: 511: 45.93		PIWI_DROME (31-811): 0: 579: 22.20
+	Dm
		284349 FMR1_DROME (1-334): 6.97e-178: 511: 45.93		AUB_DROME (22-813): 0: 576: 21.33