HitPredict

Interactor 1: SDS3 (Q8BR65)
Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog)
Gene: Suds3

Interactor 2: SDS3 (Q8BR65)
Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog)
Gene: Suds3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.608

The method score is based on:

Property	Details
Experiments	15489224, 11909966
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0001835 - blastocyst hatching GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0006915 - apoptotic process and 7 others more... GO:0030336 - negative regulation of cell migration GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway GO:0042826 - histone deacetylase binding GO:0045892 - negative regulation of DNA-templated transcription GO:0070822 - Sin3-type complex GO:1902455 - negative regulation of stem cell population maintenance GO:1902459 - positive regulation of stem cell population maintenance
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	328
Mm

1	328

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024