HitPredict

Interactor 1: PK3CB (Q8BTI9)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta) (Serine/threonine protein kinase PIK3CB) (EC 2.7.11.1)
Gene: Pik3cb

Interactor 2: FAK2 (Q9QVP9)
Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)
Gene: Ptk2b

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 19416922
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002931 - response to ischemia
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0010595 - positive regulation of endothelial cell migration
GO:0045429 - positive regulation of nitric oxide biosynthetic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1064
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024