HitPredict

Interactor 1: FLNA (Q8BTM8)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: FNDC5 (Q8K4Z2)
Fibronectin type III domain-containing protein 5 (Fibronectin type III repeat-containing protein 2) (Peroxisomal protein) (PeP) [Cleaved into: Irisin]
Gene: FNDC5

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CH~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2647 Mm			1 209
+	Mm
		1194438 FLNB_MOUSE (28-2647): 0: 2354: 68.56		FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00
+	Mm
		1225362 FLNC_MOUSE (8-2647): 0: 1231: 35.48		FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00
+	Mm
		885089 ACTN4_MOUSE (24-268): 1.36e-104: 361: 35.74		FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00
+	Mm
		984805 PGBM_MOUSE (255-1060): 7.34e-34: 146: 12.37		FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00
+	Hs
		957551 PGBM_HUMAN (273-1060): 1.03e-35: 152: 13.24		FNDC5_HUMAN (2-209): 4.81e-142: 396: 97.62