HitPredict

Interactor 1: PWP2 (Q8BU03)
Periodic tryptophan protein 2 homolog
Gene: PWP2

Interactor 2: EED (Q921E6)
Polycomb protein EED
Gene: EED

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 919 Mm			1 441
+	Hs
		268105 PWP2_HUMAN (1-918): 0: 612: 89.43		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1207948 TBL3_MOUSE (105-879): 1.16e-106: 350: 14.08		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		1206544 WDR3_MOUSE (1-578): 2.35e-101: 339: 13.39		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		268049 TBL3_HUMAN (188-879): 7.83e-99: 329: 14.12		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		268334 WDR3_HUMAN (211-893): 3.75e-65: 238: 10.47		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		1016312 TBL3_HUMAN (188-879): 7.83e-99: 329: 14.12		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		903174 TBL3_HUMAN (188-879): 7.83e-99: 329: 14.12		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		245546 TBL1X_HUMAN (411-723): 1.42e-35: 145: 16.56		TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39
+	Hs
		245633 TBL1X_HUMAN (411-723): 1.42e-35: 145: 16.56		TBL1R_HUMAN (4-335): 2.6e-56: 195: 11.40
+	Hs
		1288390 WDR3_HUMAN (211-893): 3.75e-65: 238: 10.47		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		903418 WDR5_HUMAN (585-783): 1.65e-32: 131: 10.00		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		245630 TBL1X_HUMAN (411-723): 1.42e-35: 145: 16.56		TBL1Y_HUMAN (277-439): 5.06e-19: 91.1: 13.33
+	Hs
		197071 PRP4_HUMAN (98-400): 1.54e-32: 135: 14.70		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		903428 WDR5_HUMAN (585-783): 1.65e-32: 131: 10.00		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		903349 WDR5_HUMAN (585-783): 1.65e-32: 131: 10.00		WDR5B_HUMAN (279-439): 2.9e-21: 96.1: 12.27
+	Hs
		196984 PRP4_HUMAN (98-400): 1.54e-32: 135: 14.70		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		792949 WDR5_HUMAN (585-783): 1.65e-32: 131: 10.00		LIS1_HUMAN (332-438): 2.37e-14: 76.5: 18.69
+	Hs
		903077 WDR5_HUMAN (585-783): 1.65e-32: 131: 10.00		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		196910 PRP4_HUMAN (98-400): 1.54e-32: 135: 14.70		PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51