HitPredict

Interactor 1: ARRB1 (Q8BWG8)
Beta-arrestin-1 (Arrestin beta-1)
Gene: ARRB1

Interactor 2: ARRB2 (Q91YI4)
Beta-arrestin-2 (Arrestin beta-2)
Gene: ARRB2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 19122674
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Arrestin_C~Arrestin_C, Arrestin_C~Arrestin_N, Arrestin_N~Arrestin_N
Common GO terms GO:0001933 - negative regulation of protein phosphorylation
GO:0001934 - positive regulation of protein phosphorylation
GO:0002031 - G protein-coupled receptor internalization
GO:0002092 - positive regulation of receptor internalization
GO:0005768 - endosome
and 17 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 418
Mm

1 410
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Bt
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024