HitPredict

Interactor 1: HDAC7 (Q8C2B3)
Histone deacetylase 7 (HD7) (EC 3.5.1.98) (Histone deacetylase 7A) (HD7a) (Protein deacetylase HDAC7) (EC 3.5.1.-)
Gene: HDAC7

Interactor 2: MEF2C (Q8CFN5)
Myocyte-specific enhancer factor 2C (Myocyte enhancer factor 2C)
Gene: MEF2C

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	15102471
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 938 Mm			1 474
+	Hs
		987223 HDAC7_HUMAN (23-938): 0: 638: 83.85		MEF2C_HUMAN (1-474): 2.31e-100: 310: 98.73
+	Mm
		1157743 HDAC4_MOUSE (33-921): 0: 611: 44.87		MEF2C_MOUSE (1-474): 1.75e-102: 316: 100.00
+	Hs
		880693 HDAC4_HUMAN (33-921): 0: 599: 45.85		MEF2C_HUMAN (1-474): 2.31e-100: 310: 98.73
+	Mm
		1141852 HDAC7_MOUSE (1-938): 0: 684: 100.00		MEF2A_MOUSE (1-474): 8.21e-63: 213: 55.69
+	Hs
		987233 HDAC9_HUMAN (33-879): 0: 582: 41.17		MEF2C_HUMAN (1-474): 2.31e-100: 310: 98.73
+	Mm
		1112770 Q3UJF1_MOUSE (33-936): 0: 555: 39.59		MEF2C_MOUSE (1-474): 1.75e-102: 316: 100.00
+	Hs
		968793 HDAC7_HUMAN (23-938): 0: 638: 83.85		MEF2A_HUMAN (1-474): 5.08e-63: 214: 54.63
+	Mm
		1144399 HDAC4_MOUSE (33-921): 0: 611: 44.87		MEF2D_MOUSE (1-472): 7.92e-68: 227: 49.13
+	Rn
		292567 HDAC4_RAT (33-921): 0: 610: 45.19		MEF2D_RAT (1-472): 1.89e-65: 221: 48.46
+	Hs
		880729 HDAC4_HUMAN (33-921): 0: 599: 45.85		MEF2D_HUMAN (1-472): 1.34e-68: 229: 48.67
+	Mm
		1141851 HDAC4_MOUSE (33-921): 0: 611: 44.87		MEF2A_MOUSE (1-474): 8.21e-63: 213: 55.69
+	Hs
		880686 HDAC4_HUMAN (33-921): 0: 599: 45.85		MEF2A_HUMAN (1-474): 5.08e-63: 214: 54.63
+	Hs
		968804 HDAC9_HUMAN (33-879): 0: 582: 41.17		MEF2A_HUMAN (1-474): 5.08e-63: 214: 54.63
+	Hs
		515573 HDAC4_HUMAN (33-921): 0: 599: 45.85		SRF_HUMAN (2-376): 3.71e-53: 188: 18.62
+	Mm
		1112760 Q3UJF1_MOUSE (33-936): 0: 555: 39.59		MEF2D_MOUSE (1-472): 7.92e-68: 227: 49.13
+	Mm
		1144403 HDAC5_MOUSE (33-936): 1.05e-180: 554: 39.69		MEF2D_MOUSE (1-472): 7.92e-68: 227: 49.13
+	Mm
		1112756 Q3UJF1_MOUSE (33-936): 0: 555: 39.59		MEF2A_MOUSE (1-474): 8.21e-63: 213: 55.69
+	Hs
		880687 HDAC4_HUMAN (33-921): 0: 599: 45.85		MEF2B_HUMAN (1-428): 1.26e-46: 167: 32.01
+	Hs
		968805 HDAC5_HUMAN (33-936): 7.02e-179: 550: 39.40		MEF2A_HUMAN (1-474): 5.08e-63: 214: 54.63
+	Hs
		968817 HDAC9_HUMAN (33-879): 0: 582: 41.17		MEF2B_HUMAN (1-428): 1.26e-46: 167: 32.01