HitPredict

Interactor 1: PIAS2 (Q8C5D8)
E3 SUMO-protein ligase PIAS2 (EC 2.3.2.27) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting zinc finger protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2) (RING-type E3 ubiquitin transferase PIAS2)
Gene: PIAS2

Interactor 2: TRI32 (Q8CH72)
E3 ubiquitin-protein ligase TRIM32 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM32) (Tripartite motif-containing protein 32)
Gene: Trim32

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	16816390
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008270 - zinc ion binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 621 Mm			1 655
+	Mm
		292453 PIAS1_MOUSE (1-621): 0: 575: 53.80		TRI32_MOUSE (1-655): 5.5e-163: 484: 100.00
+	Hs
		278217 PIAS2_HUMAN (1-621): 0: 702: 98.07		TRI27_HUMAN (7-476): 5.4e-99: 314: 15.50
+	Hs
		1023368 PIAS3_HUMAN (1-576): 1.85e-177: 519: 57.98		TRI32_HUMAN (1-655): 1.02e-165: 491: 96.03
+	Hs
		1023297 PIAS4_HUMAN (2-499): 3.45e-162: 475: 43.18		TRI32_HUMAN (1-655): 1.02e-165: 491: 96.03
+	Hs
		278302 PIAS2_HUMAN (1-621): 0: 702: 98.07		TRI50_HUMAN (7-475): 4.74e-77: 256: 12.97
+	Mm
		1208469 PIAS4_MOUSE (2-499): 3.78e-160: 470: 43.61		TRI32_MOUSE (1-655): 5.5e-163: 484: 100.00
+	Hs
		277914 PIAS1_HUMAN (1-621): 0: 566: 53.50		TRI27_HUMAN (7-476): 5.4e-99: 314: 15.50
+	Hs
		278162 PIAS1_HUMAN (1-621): 0: 566: 53.50		TRIM5_HUMAN (7-528): 1.05e-88: 286: 14.05
+	Hs
		537154 PIAS3_HUMAN (1-576): 1.85e-177: 519: 57.98		TRI27_HUMAN (7-476): 5.4e-99: 314: 15.50
+	Hs
		278189 PIAS1_HUMAN (1-621): 0: 566: 53.50		TRI35_HUMAN (1-488): 8.35e-76: 253: 15.64
+	Hs
		536921 PIAS4_HUMAN (2-499): 3.45e-162: 475: 43.18		TRI27_HUMAN (7-476): 5.4e-99: 314: 15.50
+	Hs
		135032 PIAS4_HUMAN (2-499): 3.45e-162: 475: 43.18		TRI38_HUMAN (7-473): 1.15e-87: 283: 15.00
+	Hs
		1318360 PIAS3_HUMAN (1-576): 1.85e-177: 519: 57.98		TRIM8_HUMAN (14-515): 1.86e-58: 207: 15.44