HitPredict

Interactor 1: Q8C5V7 (Q8C5V7)
Rap guanine nucleotide exchange factor 1
Gene: Rapgef1

Interactor 2: RHOQ (Q8R527)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10)
Gene: RHOQ

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11309621
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RasGEF, Ras~RasGEF_N
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 642 Mm			1 205
+	Hs
		925267 RPGF1_HUMAN (1-642): 0: 659: 85.38		RAC1_HUMAN (10-195): 3.63e-78: 233: 63.44
+	Hs
		892362 RPGF1_HUMAN (1-642): 0: 659: 85.38		RAC3_HUMAN (10-183): 2.94e-74: 223: 66.09
+	Hs
		950984 RPGF1_HUMAN (1-642): 0: 659: 85.38		RHOG_HUMAN (9-204): 2.29e-73: 221: 52.04
+	Mm
		650205 RGRF1_MOUSE (107-632): 4.92e-132: 419: 22.62		RHOA_MOUSE (1-204): 5.4e-75: 225: 49.51
+	Hs
		925226 SOS1_HUMAN (196-642): 5.2e-116: 378: 22.13		RAC1_HUMAN (10-195): 3.63e-78: 233: 63.44
+	Hs
		156394 RGRF2_HUMAN (112-632): 8.68e-102: 338: 20.52		CDC42_HUMAN (9-193): 5.39e-80: 238: 67.03
+	Hs
		156397 RGRF2_HUMAN (112-632): 8.68e-102: 338: 20.52		RAC1_HUMAN (10-195): 3.63e-78: 233: 63.44
+	Hs
		156395 RGRF2_HUMAN (112-632): 8.68e-102: 338: 20.52		RHOA_HUMAN (1-201): 8.27e-75: 225: 50.25
+	Hs
		171545 RGL2_HUMAN (244-641): 8.21e-100: 323: 23.25		RAC1_HUMAN (10-195): 3.63e-78: 233: 63.44
+	Hs
		893950 GNDS_HUMAN (380-642): 5.39e-77: 265: 26.49		CDC42_HUMAN (9-193): 5.39e-80: 238: 67.03
+	Hs
		951052 RGPS1_HUMAN (399-640): 3.23e-73: 247: 28.96		RHOG_HUMAN (9-204): 2.29e-73: 221: 52.04
+	Hs
		915859 RPGF6_HUMAN (408-576): 3.9e-19: 94.4: 34.46		RHOB_HUMAN (1-204): 1.08e-73: 222: 50.00