Interactor 1: PLCG2 (Q8CIH5)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-gamma-2) (PLC-gamma-2)
Gene: PLCG2

Interactor 2: BLNK (Q9QUN3)
B-cell linker protein (B-cell adapter containing a SH2 domain protein) (B-cell adapter containing a Src homology 2 domain protein) (Cytoplasmic adapter protein) (Lymphocyte antigen 57) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65)
Gene: BLNK

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 19150402
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C2~SH2, SH2~SH2, SH2~SH3_1
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0010628 - positive regulation of gene expression
GO:0035556 - intracellular signal transduction
GO:0050853 - B cell receptor signaling pathway
and 1 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1265
Mm

1 457
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024