HitPredict

Interactor 1: CAR11 (Q8CIS0)
Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 1) (Carma 1)
Gene: Card11

Interactor 2: BCL10 (Q9Z0H7)
B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CARD-containing molecule enhancing NF-kappa-B) (CARD-like apoptotic protein) (mCLAP) (CED-3/ICH-1 prodomain homologous E10-like regulator) (mCIPER) (Cellular homolog of vCARMEN) (cCARMEN) (Cellular-E10) (c-E10) (Mammalian CARD-containing adapter molecule E10) (mE10)
Gene: BCL10

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.817

The method score is based on:

Property	Details
Experiments	26936881, 18227156, 21157432
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	CARD~CARD
Common GO terms	GO:0001772 - immunological synapse GO:0005737 - cytoplasm GO:0007249 - canonical NF-kappaB signal transduction GO:0032449 - CBM complex GO:0043123 - positive regulation of canonical NF-kappaB signal transduction and 6 others more... GO:0045121 - membrane raft GO:0050700 - CARD domain binding GO:0050862 - positive regulation of T cell receptor signaling pathway GO:0050870 - positive regulation of T cell activation GO:0051092 - positive regulation of NF-kappaB transcription factor activity GO:0051260 - protein homooligomerization
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	1159
Mm

1	233

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024