Interactor 1: PBP2A (Q8DNB6)
Penicillin-binding protein 2a (PBP2a) (Cell wall synthase PBP2a) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.99.28) (Peptidoglycan TGase) (Peptidoglycan glycosyltransferase); Penicillin-sensitive transpeptidase (EC 3.4.16.4) (DD-transpeptidase)]
Gene: PBP2A

Interactor 2: PBP2A (Q8DNB6)
Penicillin-binding protein 2a (PBP2a) (Cell wall synthase PBP2a) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.99.28) (Peptidoglycan TGase) (Peptidoglycan glycosyltransferase); Penicillin-sensitive transpeptidase (EC 3.4.16.4) (DD-transpeptidase)]
Gene: PBP2A

Species: Streptococcus pneumoniae R6

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 30651563, 22487093
Identification Methods two hybrid, cross-linking study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Transgly~Transgly, Transgly~Transpeptidase, Transpeptidase~Transpeptidase
Common GO terms GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0006508 - proteolysis
GO:0008360 - regulation of cell shape
GO:0008658 - penicillin binding
and 6 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 731
Sp

1 731
+ Bs
+ Ss
+ Ss
+ Aa
+ Ec
+ Ss
+ Ss
+ Sa
+ Sa
+ Ec
+ Ec
+ Ss
+ Ec
+ Sa
+ Sa

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Last updated: 15 Jul 2024