HitPredict

Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: CALL5 (Q9NZT1)
Calmodulin-like protein 5 (Calmodulin-like skin protein)
Gene: CALML5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	24725412
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2527 Hs			1 146
+	At
		1057417 CLV1_ARATH (801-1610): 6.55e-142: 472: 14.39		CDPK1_ARATH (1-145): 5.08e-46: 159: 36.05
+	At
		103556 RGI4_ARATH (803-1479): 5.15e-141: 473: 15.78		CALM7_ARATH (1-146): 3.31e-48: 153: 45.64
+	At
		103557 RGI4_ARATH (803-1479): 5.15e-141: 473: 15.78		CALM6_ARATH (1-146): 4.95e-48: 153: 45.64
+	At
		103554 RGI4_ARATH (803-1479): 5.15e-141: 473: 15.78		CML10_ARATH (1-143): 8.35e-29: 105: 40.56
+	At
		103549 RGI4_ARATH (803-1479): 5.15e-141: 473: 15.78		CML8_ARATH (5-143): 6.18e-28: 102: 42.25
+	At
		103553 RGI4_ARATH (803-1479): 5.15e-141: 473: 15.78		CML12_ARATH (4-98): 5.42e-09: 55.1: 30.53
+	At
		515566 CRK40_ARATH (1878-2162): 4.04e-85: 296: 29.28		CALM4_ARATH (1-146): 2.78e-48: 154: 46.31
+	At
		1043105 CRK40_ARATH (1878-2162): 4.04e-85: 296: 29.28		CALM6_ARATH (1-146): 4.95e-48: 153: 45.64
+	At
		947593 CRK40_ARATH (1878-2162): 4.04e-85: 296: 29.28		CALM7_ARATH (1-146): 3.31e-48: 153: 45.64
+	At
		1182318 PXL1_ARATH (1880-2156): 1.27e-71: 264: 21.20		CDPK5_ARATH (1-145): 1.66e-45: 157: 35.37
+	At
		718325 CRK40_ARATH (1878-2162): 4.04e-85: 296: 29.28		CML10_ARATH (1-143): 8.35e-29: 105: 40.56
+	At
		200314 CRK40_ARATH (1878-2162): 4.04e-85: 296: 29.28		CML8_ARATH (5-143): 6.18e-28: 102: 42.25
+	At
		668872 Y1343_ARATH (1868-2199): 9.82e-89: 311: 26.94		CML12_ARATH (4-98): 5.42e-09: 55.1: 30.53
+	At
		668870 CRK40_ARATH (1878-2162): 4.04e-85: 296: 29.28		CML12_ARATH (4-98): 5.42e-09: 55.1: 30.53
+	Hs
		692847 MFHA1_HUMAN (845-1055): 6.1e-12: 73.9: 14.22		CALL3_HUMAN (1-146): 1.7e-48: 154: 45.64
+	Zm
		28205 A0A1D6JP61_MAIZE (1833-2136): 1.67e-24: 114: 29.18		B4FY36_MAIZE (5-143): 1.39e-25: 97.1: 40.85